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M94A2406.TXT
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Document 2406
DOCN M94A2406
TI Prevalence of non-progression of immunodeficiency in women with HIV
infection.
DT 9412
AU Carpenter CC; Flanigan TP; Mayer KH; Brown University, Providence, RI
02906.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):311 (abstract no. PC0175). Unique
Identifier : AIDSLINE ICA10/94370169
AB OBJECTIVE: To determine the prevalence of non-progression of
immunodeficiency in North American women with HIV infection. METHODS: 94
asymptomatic women living with HIV infection were followed closely for
periods of 3 to 7 yr (mean 4.1 yr). All had initial CD4 counts > 200
cells/mm3. Patients had CD4 counts at 6 month intervals. Intercurrent
health problems were treated by standard regimens. 29% of women acquired
HIV via sex, 71% via injecting drug use. Ethnic backgrounds were:
Caucasian 68%; African-American 20%, Latina 12%. RESULTS: The median
change in CD4 count was -50 cells/yr (range -477 to +73). 25 women had
decreases in CD4 counts less than 15 cells/yr. All 25 remained
asymptomatic, and their mean CD4 count increased by 14 cells per/yr. 7
of the 25 women had documented HIV infection for over 6 yr. Ethnic
backgrounds and modes of transmission did not differ from those in the
69 women whose CD4 counts fell at a greater rate. DISCUSSION &
CONCLUSIONS: 27% of 94 women with HIV infection showed no decline of CD4
count and no symptoms related to immunodeficiency over a 3 to 7 yr
period. The data indicate that long periods of immunologic stability are
not uncommon among HIV-infected women.
DE Female Follow-Up Studies Human HIV Infections/*IMMUNOLOGY Leukocyte
Count T4 Lymphocytes MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).